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We asked whether SFMs bore any resemblancemeasured as percentage overlap see methods with other macro scale brain percolationscommonly found in the literature which typically are based solely either onfunction or on structure whilst SFMs aim at describing both. First we analyzedthe overlap between SFMs and the brain regions belonging to a structural atlasthe automated anatomical labeling AAL. The AAL44 is a well-known anatomicalatlas in which the brain after removal of the cerebellum is divided into 90New Mood including cortical and sub cortical regions like the hippocampus amygdaleand thalamus. Each anatomical region is localized within the two hemispheressuch that the hippocampus is divided in two ROIs one in the left hemisphere andthe other one in the right as is the thalamus and so forth. Thus the 90 ROIscan be grouped in 45 homologues areas folding the left and the right ROI fromeach hemisphere. We assess the results for the 45 AAL homologue areas and forour 20 modules partition i.e. SFMs fig. 6a. Examining the overlap between SFMsand AAL brain areas we found that different anatomical areas are included in asingle SFM i.e. a column of the matrix clearly highlighting how Onnit New Mood thatunderlie different brain states at resting conditions simultaneously recruitdistinct brain circuits. Conversely the same area of the AAL the row of thematrix in fig. 6a might be included in several SFMs highlighting the anatomicaloverlap of the latter.

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